Nanotechnology in vaccine delivery

*Corresponding author Dr. Wahid Khan, Ph.D Assistant Professor Department of Pharmaceutics National Insititute of Pharmaceutical Education and Research Balanagar, Hyderabad 500 037, Andhra Pradesh, INDIA E-Mail: [email protected] ABSTRACT Success of vaccination in dealing with the communicable diseases can be clearly understood by eradication of smallpox and the imminent decrease of polio, and also the Expanded Program for Immunization (EPI) leaded by The World Health Organization succeeded dramatically to meet its target to furnish six major diseases of children (diphtheria, pertuasis, tetanus, polio, measles, and tuberculosis. Despite these impressive achievements, significant problems are still present for development of a breakthrough vaccine for diseases like cancer, HIV, influenza and even though vaccines has being developed for some diseases its mass commercialization is a big challenge. Nanotechnology, which is a cutting-edge area of present research, gave new dimensions to vaccine world and the results came out as DNA vaccine, conjugate vaccine and many more advancements. This brief review will put some light upon the enormous scope of nanotechnology in vaccine delivery also new advancement in terms of route for vaccine delivery with recent marketed products in clinical use. Briefly, challenges for commercialization of vaccines worldwide are also discussed.